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Table 2 Pre- and post-intervention blood biomarker absolute outcome values and percentage change

From: Resistance training's impact on blood biomarkers and cognitive function in older adults with low and high risk of mild cognitive impairment: a randomized controlled trial

 

Group

N

Pre-Intervention

Post-Intervention

Δ (%)

IGF-1 (ng/mL)

EXP

24

119.0 (57.6)

139.2 (85.4)

 + 17.0

-hrMCI

12

118.0 (55.2)

143.2 (81.2)

 + 21.4

-lrMCI

12

120.1 (62.4)

135.3 (92.8)

 + 12.7

CON

18

112.5 (50.2)

136.3 (66.4)

 + 21.2

-hrMCI

8

117.7 (58.3)

141.3 (58.3)

 + 20.1

-lrMCI

10

108.3 (45.5)

132.4 (75.1)

 + 22.2

Total

42

116.2 (54.0)

138.0 (77.0)

 + 18.8

-hrMCI

20

117.9 (54.9)

142.4 (71.2)

 + 20.8

-lrMCI

22

114.7 (54.4)

133.9 (83.3)

 + 16.7

IL-6 (pg/mL)

EXP

23

8.5 (9.2)

12.2 (12.2)

 + 43.5

-hrMCI

12

6.7 (5.5)

10.3 (11.2)

 + 53.7

-lrMCI

11

10.5 (12.0)

14.4 (13.5)

 + 37.1

CON

20

7.7 (8.2)

7.2 (8.9)

-6.5

-hrMCI

10

4.5 (4.2)

4.1 (3.1)

-8.9

-lrMCI

10

11.2 (10.2)

10.7 (11.8)

-4.5

Total

43

8.1 (8.6)

9.9 (11.0)

 + 22.2

-hrMCI

22

5.6 (4.9)

7.3 (8.8)

 + 30.4

-lrMCI

21

10.8 (10.9)

12.7 (12.6)

 + 17.6

KYN (ng/mL)

EXP

23

1582.3 (755.7)

1301.3 (606.4)

-17.8

-hrMCI

11

1434.8 (650.6)

1442.3 (579.5)

 + 0.5

-lrMCI

12

1717.4 (846.1)

1172.2 (626.2)

 + 46.5

CON

22

1616.4 (709.1)

1507.1 (578.2

-6.8

-hrMCI

12

1308.2 (441.0)

1722.2 (593.8)

 + 31.6

-lrMCI

10

2017.2 (808.8)

1227.5 (439.8)

-39.1

Total

45

1599.3 (724.8)

1404.2 (595.0)

-12.2

-hrMCI

23

1366.2 (538.2)

1593.9 (591.8)

 + 16.7

-lrMCI

22

1853.7 (823.8)

1197.3 (537.7)

-35.4

  1. Only the values of the participants with pre-and post-intervention measurements were used for analysis
  2. Abbreviations: CON Control, EXP Experimental, hrMCI High risk for mild cognitive impairment, IGF-1 Insulin-like growth factor-1, IL-6 Interleukin-6, KYN Kynurenine, lrMCI Low risk for mild cognitive impairment