Resistance training's impact on blood biomarkers and cognitive function in older adults with low and high risk of mild cognitive impairment: a randomized controlled trial

Table 5 Bivariate correlations between changes in blood biomarkers and cognition in experimental group

		ΔIL-6	ΔKYN	ΔANAM 2-choice reaction time	ΔANAM Go/No-go	ΔANAM Memory search	ΔANAM Mathematical processing
ΔIGF-1	R	-0.271	0.022	-0.025	0.276	-0.001	-0.497*
ΔIGF-1	p	0.210	0.922	0.907	0.192	0.997	0.014
ΔIL-6	R		0.155	-0.121	0.125	-0.289	0.254
ΔIL-6	p		0.492	0.581	0.569	0.181	0.242
ΔKYN	R			-0.004	0.004	-0.128	-0.167
ΔKYN	p			0.986	0.986	0.559	0.446
ΔANAM 2-choice reaction time	R				0.432*	0.158	0.209
ΔANAM 2-choice reaction time	p				0.025	0.431	0.296
ΔANAM Go/No-go	R					0.105	-0.206
ΔANAM Go/No-go	p					0.602	0.303
ΔANAM Memory search	R						-0.156
ΔANAM Memory search	p						0.436

Significant values are marked in bold, significance level * p < 0.05
Δ values were calculated by subtracting the post-intervention value from the pre-intervention value
Spearman’s rho correlation values are presented. Significant correlations are marked in bold
Abbreviations: ANAM Automated Neuropsychological Assessment Metrics, IGF-1 Insulin-like growth factor-1, IL-6 Interleukin-6; KYN, kynurenine

ISSN: 1861-6909