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Table 2 Function of T cells in elderly

From: Acquired immunity: immunosenescence and physical activity

Function

Reduced response to receptor stimulations and an altered proliferative capacity

Decreased IL-2 and decreased expression of IL-2 receptor

Increased production of inflammatory cytokines: TNF α, IFN γ, IL-6,TGF- β

Altered response to influenza vaccine

Reduced proliferative response to mitogens

Decreased capacity to maintain a repertoire of TCR

Decreased cytolitic activity

  1. TCR T-cell receptor, TNF α tumor necrosis factor alpha, IFN γ interferon gamma, IL-6 interleukin 6, TGF-β transforming growth factor beta
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European Review of Aging and Physical Activity

ISSN: 1861-6909

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