Variable | Intervention group (n = 78) | Control group (n = 75) |  | ||
---|---|---|---|---|---|
 | Pre | Post | Pre | Post | P a |
Primary outcome measures | Â | Â | Â | Â | Â |
 Physiological Profile Assessment (score) | 0.62 ± 0.89 | 0.41 ± 0.95 | 0.55 ± 0.90 | 0.39 ± 0.80 | 0.035 |
 European Quality of Life – 5 Dimensions (index) | 0.86 ± 0.11 | 0.86 ± 0.15 | 0.86 ± 0.13 | 0.87 ± 0.13 | 0.741 |
 European Quality of Life – 5 Dimensions (VAS) | 79.2 ± 14.7 | 80.9 ± 13.7 | 81.7 ± 12.7 | 79.9 ± 14.6 | 0.244 |
Secondary outcome measures | Â | Â | Â | Â | Â |
 General health measures | |||||
  WHODAS (score)b | 16.0 ± 4.5 | 16.3 ± 4.8 | 15.6 ± 4.1 | 16.0 ± 4.5 | 0.494 |
 Physical and sensorimotor measures | |||||
  Melbourne edge test (score) | 20.8 ± 1.6 | 21.0 ± 2.1 | 21.1 ± 1.8 | 21.2 ± 2.1 | 0.278 |
  Proprioception (°)b | 1.3 ± 1.0 | 1.2 ± 1.1 | 1.7 ± 1.3 | 1.3 ± 0.9 | 0.758 |
  Knee extension strength (kg) | 23.0 ± 9.2 | 28.0 ± 11.9 | 22.7 ± 9.9 | 27.1 ± 14.0 | 0.545 |
  Hand grip strength (kg) | 24.9 ± 9.4 | 23.8 ± 8.6 | 23.9 ± 9.0 | 24.0 ± 8.7 | 0.979 |
  Hand reaction time (ms) | 245 ± 43 | 249 ± 47 | 239 ± 50 | 263 ± 45 | 0.002 |
  Sway, area (mm2)b | 841 ± 692 | 774 ± 1191 | 797 ± 596 | 629 ± 973 | 0.940 |
  Coordinated stability, errorsb | 11.3 ± 10.3 | 8.5 ± 9.0 | 12.2 ± 13.6 | 8.0 ± 9.0 | 0.909 |
  Maximum balance range, anterior-posterior (mm) | 139 ± 41 | 145 ± 35 | 137 ± 48 | 152 ± 39 | 0.713 |
  Timed up and go test (s) | 9.7 ± 2.8 | 9.5 ± 2.7 | 10.2 ± 3.1 | 9.2 ± 2.1 | 0.504 |
  Short Physical Performance Battery (score) | 10.4 ± 1.7 | 11.1 ± 1.5 | 10.2 ± 1.6 | 10.9 ± 1.4 | 0.548 |
  Sensor-based chair stand test (s)b | 12.5 ± 4.2 | 10.8 ± 3.2 | 13.1 ± 3.7 | 12.1 ± 3.3 | 0.347 |
  Sensor-based semi tandem stance (s) | 28.3 ± 6.0 | 28.9 ± 5.2 | 29.5 ± 3.0 | 29.2 ± 4.5 | 0.412 |
  Sensor-based near tandem stance (s) | 28.1 ± 6.3 | 28.5 ± 5.7 | 28.3 ± 5.4 | 29.1 ± 4.5 | 0.876 |
  Sensor-based full tandem stance (s) | 24.4 ± 9.9 | 24.4 ± 9.5 | 23.3 ± 10.2 | 25.0 ± 9.2 | 0.727 |
  Sensor-based hand reaction time (ms)b | 698 ± 142 | 619 ± 131 | 705 ± 391 | 649 ± 162 | 0.259 |
  Sensor-based stepping reaction time (ms)b | 794 ± 199 | 732 ± 209 | 801 ± 142 | 743 ± 121 | 0.055 |
  10 m walking time, single-tasking (s)b | 8.9 ± 2.0 | 8.7 ± 1.8 | 8.9 ± 2.3 | 8.6 ± 1.8 | 0.323 |
  10 m walking time, dual-tasking (s)b | 12.0 ± 3.9 | 11.4 ± 3.8 | 12.0 ± 4.5 | 11.7 ± 4.0 | 0.040 |
 Cognitive measures | |||||
  Trail Making Test, part A (s)b | 42.8 ± 17.5 | 40.4 ± 16.5 | 44.2 ± 18.1 | 39.5 ± 14.1 | 0.736 |
  Trail Making Test, part B (s)b | 114.5 ± 55.8 | 100.6 ± 51.1 | 116.2 ± 52.2 | 96.3 ± 47.9 | 0.474 |
  Digit symbol coding test, correct (n) | 49.4 ± 15.6 | 51.4 ± 15.7 | 44.5 ± 13.0 | 48.6 ± 11.9 | 0.444 |
  Digit span backward test, score (n) | 6.0 ± 2.3 | 6.1 ± 2.1 | 5.9 ± 2.3 | 5.7 ± 2.5 | 0.178 |
  Attention Network Test, reaction time (ms)b | 808 ± 134 | 789 ± 130 | 810 ± 116 | 745 ± 97 | 0.121 |
  Attention Network Test, alert (ms) | 29.5 ± 34.3 | 37.3 ± 30.0 | 35.4 ± 33.8 | 39.1 ± 32.2 | 0.262 |
  Attention Network Test, orient (ms) | 44.4 ± 38.2 | 44.0 ± 40.1 | 51.5 ± 42.1 | 59.0 ± 40.6 | 0.561 |
  Attention Network Test, conflict (ms)b | 134.3 ± 74.7 | 117.3 ± 53.3 | 127.1 ± 60.3 | 126.7 ± 63.5 | 0.329 |
  Victoria Stroop Test, intrusions (n)b | 3.0 ± 3.4 | 2.3 ± 3.4 | 3.2 ± 4.0 | 2.6 ± 4.3 | 0.802 |
  Victoria Stroop Test, efficacy (colour words/words)b | 1.69 ± 0.73 | 1.52 ± 0.67 | 1.63 ± 0.74 | 1.48 ± 0.60 | 0.412 |
 Psychological measures | |||||
  Iconographical – Falls Efficacy Scale (score) | 16.2 ± 5.3 | 12.6 ± 8.5 | 15.4 ± 4.4 | 11.0 ± 7.5 | 0.593 |
  Patient Health Questionnaire – 9 (score)b | 3.06 ± 3.14 | 2.48 ± 2.92 | 2.99 ± 2.97 | 2.58 ± 2.38 | 0.340 |