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Table 6 Effect of exercise /physical activity on cognition

From: Exercise or physical activity and cognitive function in adults with type 2 diabetes, insulin resistance or impaired glucose tolerance: a systematic review

Citation Assessment time point Outcome measurements Results Statistics
Domain Method Group Physical activity levels Between group mean difference (95%, CIs) p-value
Colberg
et al.
2008
[36]
Cross section study Global cognitive function MMSE
SLUMS
AE
CO
AE
CO
AE
CO
weekday light activity: 5.5 ± 0.4
weekday light activity: 6.9 ± 0.3
weekday moderate activity: 3.0 ± 0.3
weekday moderate activity: 3.2 ± 0.4
weekday light activity: 5.5 ± 0.4
weekday light activity: 6.9 ± 0.3
Not reported
Not reported
Not reported
0.04
<0.01
0.04
Devore
et al.
2009 [37]
Cross section study General cognitive function
Memory
TICS score
Global cognitive
Score
Immediate and delayed recalls
LPA
MPA
HPA
LPA
MPA
HPA
LPA
MPA
HPA
3.38 (0.13–6.76)
10.70 (6.77–15.50)
24.39(15.54–112.23)
3.38 (0.13–6.76)
10.70 (6.77–15.50)
24.39(15.54–112.23)
3.38 (0.13–6.76)
10.70 (6.77–15.50)
24.39(15.54–112.23)
0.37 (0.02, 0.72)
0.07 (0.01, 0.15)
0.06 (0.03, 0.1)
0.03
(HPA versus LPA)
0.06
(HPA
versus LPA)
0.20
(HPA
versus LPA)
Devore
et al.
2009 [37]
Prospective study General cognitive function
Memory
TICS score
Global cognitive
Score
Immediate and delayed recalls
LPA
MPA
HPA
LPA
MPA
HPA
LPA
MPA
HPA
3.38 (0.13–6.76)
10.70 (6.77–15.50)
24.39(15.54–112.23)
3.38 (0.13–6.76)
10.70 (6.77–15.50)
24.39(15.54–112.23)
3.38 (0.13–6.76)
10.70 (6.77–15.50)
24.39(15.54–112.23)
0.21 (0.15, 0.57)
0.05 (0.03, 0.12)
0.07 (0.03, 0.16)
0.20
(HPA
versus LPA)
0.20
(HPA
versus LPA)
0.20
(HPA
versus LPA)
  1. Data are presented as mean ± SD and mean difference and 95% confidence intervals (CIs), adjusted for age, education, disability indicators, and others
  2. SLUMS Saint Louis University Mental Status exam, MMSE Mini-Mental State Examination, TICS Telephone Interview for Cognitive Status, LPA low physical activity, MPA moderate physical activity, HPA high physical activity, AE regular physical exercise in individuals with diabetes, CO regular physical exercise in normal individuals
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