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Table 6 Effect of exercise /physical activity on cognition

From: Exercise or physical activity and cognitive function in adults with type 2 diabetes, insulin resistance or impaired glucose tolerance: a systematic review

Citation

Assessment time point

Outcome measurements

Results

Statistics

Domain

Method

Group

Physical activity levels

Between group mean difference (95%, CIs)

p-value

Colberg

et al.

2008

[36]

Cross section study

Global cognitive function

MMSE

SLUMS

AE

CO

AE

CO

AE

CO

weekday light activity: 5.5 ± 0.4

weekday light activity: 6.9 ± 0.3

weekday moderate activity: 3.0 ± 0.3

weekday moderate activity: 3.2 ± 0.4

weekday light activity: 5.5 ± 0.4

weekday light activity: 6.9 ± 0.3

Not reported

Not reported

Not reported

0.04

<0.01

0.04

Devore

et al.

2009 [37]

Cross section study

General cognitive function

Memory

TICS score

Global cognitive

Score

Immediate and delayed recalls

LPA

MPA

HPA

LPA

MPA

HPA

LPA

MPA

HPA

3.38 (0.13–6.76)

10.70 (6.77–15.50)

24.39(15.54–112.23)

3.38 (0.13–6.76)

10.70 (6.77–15.50)

24.39(15.54–112.23)

3.38 (0.13–6.76)

10.70 (6.77–15.50)

24.39(15.54–112.23)

0.37 (0.02, 0.72)

0.07 (0.01, 0.15)

0.06 (0.03, 0.1)

0.03

(HPA versus LPA)

0.06

(HPA

versus LPA)

0.20

(HPA

versus LPA)

Devore

et al.

2009 [37]

Prospective study

General cognitive function

Memory

TICS score

Global cognitive

Score

Immediate and delayed recalls

LPA

MPA

HPA

LPA

MPA

HPA

LPA

MPA

HPA

3.38 (0.13–6.76)

10.70 (6.77–15.50)

24.39(15.54–112.23)

3.38 (0.13–6.76)

10.70 (6.77–15.50)

24.39(15.54–112.23)

3.38 (0.13–6.76)

10.70 (6.77–15.50)

24.39(15.54–112.23)

0.21 (0.15, 0.57)

0.05 (0.03, 0.12)

0.07 (0.03, 0.16)

0.20

(HPA

versus LPA)

0.20

(HPA

versus LPA)

0.20

(HPA

versus LPA)

  1. Data are presented as mean ± SD and mean difference and 95% confidence intervals (CIs), adjusted for age, education, disability indicators, and others
  2. SLUMS Saint Louis University Mental Status exam, MMSE Mini-Mental State Examination, TICS Telephone Interview for Cognitive Status, LPA low physical activity, MPA moderate physical activity, HPA high physical activity, AE regular physical exercise in individuals with diabetes, CO regular physical exercise in normal individuals