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Table 7 Relationship between changes in cognition and insulin resistance

From: Exercise or physical activity and cognitive function in adults with type 2 diabetes, insulin resistance or impaired glucose tolerance: a systematic review

Citation Cognition Insulin resistance measurement Time since last exercise bout Relationship r p-value Comments
Watson
et al.
2006 [35]
Delayed memory Two-hour Oral glucose tolerance test insulin level (mmol/L) 26 weeks Change in delayed
memory and change in two-hour Oral glucose tolerance test insulin level (mmol/L)
−0.52 0.047 Exercise group (Aerobic exercise plus American Heart Association Step 2 Eucaloric Diet only
Colberg
et al. 2008 [36]
Global cognitive function Homeostatic Model Assessment-insulin resistance
Insulin (IU/mL)
Not
reported
Not
reported
Relationship between
HOMA-IR and
cognitive function
Relationship between insulin level and cognitive function
−0.19
−0.18
0.02
0.03
Diabetes exercise group
Yanagawa et al. 2011 [39] Delayed memory Euglycemic
Clamp (glucose
infusion rate (mL/kg/min)
Metabolic clearance
rate(mL/kg/min)
12 weeks Change in word recall and change in glucose infusion rate
Change in word recall and change in metabolic clearance rate
0.64
0.575
0.024
0.051
Horseback riding simulation equipment (JOBA) exercise group
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