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Table 3 Comparison of outcomes measure scores before and after the intervention in different groups

From: Effect of 9 weeks continuous vs. interval aerobic training on plasma BDNF levels, aerobic fitness, cognitive capacity and quality of life among seniors with mild to moderate Alzheimer’s disease: a randomized controlled trial

Variables

CAT group, n = 14

IAT group, n = 17

Control group, n = 21

Pre - Training

Post - Training

Pre - Training

Post - Training

Pre - Intervention

Post - Intervention

Global cognition

 MMSE, Sub test:

  Orientation

4.5 (4–6)

6 (4.3–7)

5 (4–6)

5 (3–7)

7 (4.8–8)

5 (4–7)

  Registration

3 (3–3)

3 (3–3)

3 (3–3)

3 (3–3)

3 (3–3)

3 (3–3)

  Attention and calculation

1 (0–4)

1.5 (0–4)

2 (1–3)

1 (0–2)*

2.5 (2–4)

2 (1–4)

  Free recall

0 (0–1)

0 (0–1)

0 (0–0)

0 (0–0)

0 (0–0)

0 (0–0)

  Language

8 (7–8)

8 (7–8)

7.5 (7–8)

7 (7–8)

7.5 (7–8)

7 (7–8)

  Visual construction

1 (0.3–1)

1 (0.3–1)

1 (0–1)

0 (0–1)

1 (0–1)

1 (0–1)

MMSE, total score

18 (16–21)

20 (18.3–21)a

18 (17–19)

17 (15–21)a

21 (17–23)

19 (15–22)

Neurocognitive domain

 Memory:

  RAVLT

22 (13–26)

21.5 (15.5–25)

21 (16–25)

17 (15–24)

19 (18–24)

19 (15–20)

 Working memory:

  Forward Digit Span

5 (3–6)

5.5 (4–6)

4 (4–5.3)

5.5 (4–6)

5 (4–7)

5 (4–6)

  Backward Digit Span

2 (2–3)

3 (2.3–3)

3 (2–3)

3 (2–3)

3 (2–4)

3 (2–3)

  1. Median and range are provided unless otherwise indicated. *: intra group difference (p < 0.05). a: between group difference (p < 0.05). Abbreviation: MMSE, score: Mini-Mental State Examine, score 0 to 30 with higher score indicating better global cognition; Orientation, score 0 to 10; Registration, score 0 to 3; Attention and calculation, score 0 to 5; Free recall, score 0 to 3; Language, score 0 to 8; Visual construction, score 0 to 1; RAVLT: Rey Auditory Verbal learning Test, score 0 to 75 with higher score indicating better memory; Digit span (Forward and backward), score 0 to 9 with higher score indicating better working memory direct or indirect