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Table 3 Comparison of outcomes measure scores before and after the intervention in different groups

From: Effect of 9 weeks continuous vs. interval aerobic training on plasma BDNF levels, aerobic fitness, cognitive capacity and quality of life among seniors with mild to moderate Alzheimer’s disease: a randomized controlled trial

VariablesCAT group, n = 14IAT group, n = 17Control group, n = 21
Pre - TrainingPost - TrainingPre - TrainingPost - TrainingPre - InterventionPost - Intervention
Global cognition
 MMSE, Sub test:
  Orientation4.5 (4–6)6 (4.3–7)5 (4–6)5 (3–7)7 (4.8–8)5 (4–7)
  Registration3 (3–3)3 (3–3)3 (3–3)3 (3–3)3 (3–3)3 (3–3)
  Attention and calculation1 (0–4)1.5 (0–4)2 (1–3)1 (0–2)*2.5 (2–4)2 (1–4)
  Free recall0 (0–1)0 (0–1)0 (0–0)0 (0–0)0 (0–0)0 (0–0)
  Language8 (7–8)8 (7–8)7.5 (7–8)7 (7–8)7.5 (7–8)7 (7–8)
  Visual construction1 (0.3–1)1 (0.3–1)1 (0–1)0 (0–1)1 (0–1)1 (0–1)
MMSE, total score18 (16–21)20 (18.3–21)a18 (17–19)17 (15–21)a21 (17–23)19 (15–22)
Neurocognitive domain
 Memory:
  RAVLT22 (13–26)21.5 (15.5–25)21 (16–25)17 (15–24)19 (18–24)19 (15–20)
 Working memory:
  Forward Digit Span5 (3–6)5.5 (4–6)4 (4–5.3)5.5 (4–6)5 (4–7)5 (4–6)
  Backward Digit Span2 (2–3)3 (2.3–3)3 (2–3)3 (2–3)3 (2–4)3 (2–3)
  1. Median and range are provided unless otherwise indicated. *: intra group difference (p < 0.05). a: between group difference (p < 0.05). Abbreviation: MMSE, score: Mini-Mental State Examine, score 0 to 30 with higher score indicating better global cognition; Orientation, score 0 to 10; Registration, score 0 to 3; Attention and calculation, score 0 to 5; Free recall, score 0 to 3; Language, score 0 to 8; Visual construction, score 0 to 1; RAVLT: Rey Auditory Verbal learning Test, score 0 to 75 with higher score indicating better memory; Digit span (Forward and backward), score 0 to 9 with higher score indicating better working memory direct or indirect