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Table 1 Descriptive characteristics and findings of included studies in stroke subcategory

From: The effects of virtual reality training in stroke and Parkinson’s disease rehabilitation: a systematic review and a perspective on usability

 

Sample

Intervention

Comparison

Outcome

Test

Results

Conclusion

User feedback / follow-up info

[29]

Adomaviciene 2019

RCT

N=42

Subacute

Mean age= 64.6

VR Kinect + conventional

2 weeks

5 times/ week

Conventional with robot-assisted trainer “Armeo Spring”

2 weeks

5 times/ week

UE mobility

Function*

Psycho-emotional

FMA, MAS

BBT, HTT

ROM, FIM

HAD

No between group difference in FIM, but p<0.05 in self-care in VR.

UE function significant improvement p<0.05 in both groups

VR p<0.05 in HAD

Both groups improved in function, UE mobility and cognitive abilities.

Great user satisfaction, improved psycho-emotional state in VR/ No follow-up

[20]

Fishbein 2019

RCT

N=22

Chronic

Mean age= 65.2

VR dual task walking

4weeks

2 times/ week

Conventional treadmill single task walking

4weeks

2 times/ week

Gait

Balance Function

10MWT, TUG FRT, BBS

ABC

VR p<0.01 in BBS, FRT, 10MWT, ABC

VR is effective in improvement of balance, gait and function. Advised combination with conventional training with multitasking

Follow-up 4 weeks – effect maintained

[32]

Kiper 2018

RCT

N = 136

Chronic, subacute

Mean age= 63.9

VR + conventional

4 weeks

5 times/week

Conventional

4 weeks

5 times/week

UE mobility

Function

FMA

FIM

NIHSS

ESAS

VR + conventional p<0.05 in all outcomes

VR combined with conventional has greater effect on UE function

No follow-up

[33]

Askin 2018

RCT

N=40

Chronic

Mean age= 54.9

VR Kinect + conventional

4 weeks

5 times/week

Conventional

4 weeks

5 times/week

UE mobility

Function

FMA, MAS

BBT, MI

ROM

VR p<0.05 in all outcomes

Between group difference VR p<0.05 in FMA, MI, ROM

VR as an effective addition to conventional therapy for UE function and ROM improvement

Good response to VR, great user satisfaction/ No follow-up

[31]

Lee MM 2018

RCT

N= 30

Subacute

Mean age= 61.6

VR Wii + conventional

5 weeks

3 times/week

Conventional

5 weeks

3 times/week

UE function

Balance

MFT

FRT

Both groups p<0.05 in all outcomes.

Between group difference p<0.05 in VR in balance, UE function

VR is effective for postural balance and UE function if combined with conventional

No follow-up

[34]

Schuster-Ampf 2018

RCT

N = 54

Chronic

Mean age = 61.2

VR

4 weeks

4 times/week

Conventional

4 weeks

4 times/week

UE function

Dexterity

QoL

ADL

BBT

CAHAI

SIS

BI

Both groups p<0.05 in BBT, CAHAI, SIS

No between group difference in all outcomes, except for SIS p<0.05 in VR

VR as an effective alternative to conventional therapy in UE function, ADL, QoL.

Groups improved more in first 2 weeks.

Greater improvement and response to VR in less impaired / No follow-up

[21]

Utkan-Karasu 2018

RCT

N=23

Chronic, subacute

Mean age= 63.2

VR Wii

4 weeks

5 times/week

Conventional

4 weeks

5 times/week

Balance

Function

BBS, FRT

FIM, TUG

Both groups p<0.05 in all outcomes

Between group difference VR p<0.05 in BBS, FRT, FIM

VR is an effective additional intervention for improvement of function, balance, independence

Follow-up 4 weeks – effect maintained

[22]

Lee HC 2017

RCT

N= 47

Chronic

Mean age= 57.6

VR Kinect + conventional

6 weeks

2 times/week

Conventional

6 weeks

2 times/week

Balance

ADL

QoL

Satisfaction, feasibility

BBS, FRT, TUG BI, ABC

SIS

Both groups p<0.05 in BBS, TUG

No between group difference in other outcomes

VR combined with conventional is effective for balance training

Great user satisfaction in VR/

Follow-up 3 months – effect maintained

[35]

Brunner 2017

RCT

N=112

Subacute

Mean age= 62

VR

4 weeks4 times/week

Conventional

4 weeks

4 times/week

UE mobility

Function

ADL

ARAT

BBT

FIM

Both groups p<0.01 in all outcomes

No between group difference

VR as effective as conventional for UE function. Entertaining alternative to standard rehabilitation

Great user satisfaction in VR/

Follow-up 3 months – effect maintained

[25]

Adie 2017

RCT

N=209

Subacute

Mean age= 67.3

VR Wii

6 weeks

7 times/week

Conventional

6 weeks

7 times/week

UE mobility

Function

QoL

Cost-effect

ARAT

MRS

SIS

EQ-5D-3L

Both groups p<0.05 in ARAT, EQ 5D 3L

No between group difference

VR not superior than conventional, but exciting.

Cost-effect - more expensive than home exercise.

Good acceptability of VR/

Follow-up 6 months – no between group difference, but improved health state and arm function

  1. *Function here refers to general functional ability, motor function by functional assessment tools. The terminology varies between the studies
  2. Abbreviations: 10MWT 10 meter Walk Test, ABC Activity-specific BalanceConfidence scale, ARAT Action Research Arm Test, BBS Berg Balance Scale, BBT Box and Block Test, BI Barthel Index, CAHAI Chedoke McMaster Arm and Hand Activity Inventory, ESAS Edmonton Symptom Assessment Scale, EQ-5D-3L Quality of Life measure, FIM Functional Independence Measure, FMA Fugl-Meyer Assessment, FRT Functional Reach Test, HAD Hospital Anxiety and Depression scale, HTT Hand-Tapping Test, MAS Modified Ashworth Scale, MI Motricity Index, MFT Manual Function Test, MRS Modified Rankin Scale, NIHSS National Institute of Health Stroke Scale, ROM Range of Motion, SIS Stroke Impact Scale, TUG Timed Up and Go test, UE upper extremity