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Table 2 Association of movement behaviors with cardiac biomarkers in men and women, stratified by subclinical cardiac damage and PA time

From: Device-measured movement behaviors and cardiac biomarkers in older adults without major cardiovascular disease: the Seniors-ENRICA-2 study

 

Men

Women

 

No subclinical cardiac damageb

Subclinical cardiac damageb

No subclinical cardiac damageb

Subclinical cardiac damageb

 

Low PA timec

n = 267

High PA timec

n = 234

Low PA timec

n = 190

High PA timec

n = 169

Low PA timec

n = 171

High PA timec

n = 218

Low PA timeb

n = 342

High PA timec

n = 348

hs-cTnT

 Sleep

− 0.6 (− 2.4, 1.3)

− 0.4 (− 2.7, 1.9)

− 1.7 (− 3.6, 0.2)

− 0.9 (− 3.6, 1.9)

 0.1 (− 2.2, 2.4)

− 0.4 (− 3.0, 2.2)

− 0.4 (− 2.0, 1.2)

− 2.3 (− 4.1, − 0.4)

 SB

  0.2 (− 1.4, 1.9)

  0.1 (− 1.8, 2.0)

   3.3 (1.4, 5.1)

− 0.7 (− 2.9, 1.4)

− 1.1 (− 3.4, 1.2)

− 1.0 (− 3.0, 0.9)

    2.1 (0.7, 3.6)d

− 1.5 (− 0.1, 3.1)

 LPA

  1.9 (− 2.4, 6.5)

  1.0 (− 3.1, 5.2)

− 3.9 (− 8.4, 0.8)

   2.3 (− 1.9, 6.7)

   2.2 (− 2.7, 7.3)

   2.8 (− 0.8, 6.6)

− 5.1 (− 8.3, − 1.7)d

    4.1 (1.2, 7.2)d

 MVPA

− 1.1 (− 7.0, 5.3)

− 0.2 (− 4.0, 3.8)

 − 13.1 (− 18.3, − 7.5)d

   3.4 (− 1.3, 8.2)

   6.4 (− 2.3, 16.0)

   1.8 (− 2.0, 5.7)

− 17.5 (− 22.9, − 11.7)d

− 5.4 (− 8.7, − 2.0)d

NT-proBNP

 Sleep

   1.5 (− 1.6, 4.7)

   2.2 (− 1.7, 6.3)

− 0.8 (− 3.9, 2.5)

− 2.0 (− 6.5, 2.6)

   0.2 (− 3.5, 4.1)

   0.6 (− 3.7, 5.0)

   2.3 (− 0.3, 5.1)

   1.8 (− 1.3, 5.0)

 SB

− 1.8 (− 4.5, 1.0)

   0.2 (− 2.9, 3.5)

   5.8 (2.7, 8.9)d

− 0.6 (− 4.1, 3.0)

   0.6 (− 3.2, 4.6)

− 0.7 (− 3.9, 2.6)

− 0.6 (− 3.0, 1.8)

− 1.7 (− 4.2, 0.8)

 LPA

   8.1 (0.5, 16.2)

− 1.2 (− 7.7, 5.7)

−19.3 (− 25.4, − 12.7)d

   1.0 (− 5.8, 8.3)

− 1.6 (− 9.3, 6.7)

   3.4 (− 2.6, 9.8)

− 4.9 (− 10.1, 0.7)

   0.4 (− 4.3, 5.3)

 MVPA

−6.7 (− 15.9, 3.4)

−4.8 (− 10.8, 1.6)

−23.1 (− 30.7, − 14.6)d

   7.0 (− 0.9, 15.5)

−7.4 (− 19.8, 6.8)

− 2.1 (− 8.1, 4.3)

− 11.4 (− 20.9, − 0.8)

− 0.0 (− 5.8, 6.1)

  1. Values are mean percentage differencesa (95% confidence interval) in each cardiac biomarker per 30 min/day increment in each movement behavior in each stratum
  2. Linear regression models adjusted for sex, age, educational level (primary or less, secondary, or university), smoking status (never, former, or current), alcohol consumption (never, moderate, heavy, or former), energy intake (kcal/day), Mediterranean Diet Adherence Screener (MEDAS) score, body mass index (kg/m2), serum glucose (mg/dL), serum LDL-cholesterol (mg/dL), systolic blood pressure (mmHg) and glomerular filtration rate (mL/min)
  3. aMean percentage differences were calculated by subtracting 1 from the exponentiated β-coefficients in the regression models with log-transformed values of cardiac biomarkers and multiplying the result by 100
  4. bSubclinical cardiac damage: hs-cTnT >p99 (16.8 pg/mL in men and 9.0 pg/mL in women) and/or NT-proBNP >cutoff (75 pg/mL if age ≤ 75 years, 250 pg/mL if age > 75 years)
  5. cLow PA time: total PA time ≤ 3.53 h/day; high PA time: total PA time > 3.53 h/day
  6. dStatistically significant association when using a false discovery rate of 5%. hs-cTnT: high-sensitivity cardiac troponin T; LPA: light physical activity; MVPA: moderate-to-vigorous physical activity; NT-proBNP: N-terminal pro-B-type natriuretic peptide; PA: physical activity; SB: sedentary behavior