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Table 4 HRs and 95% CIs for the association between physical activity trajectory and cancer risk in both sexes, by smoking status

From: Trajectory of physical activity frequency and cancer risk: Findings from a population-based cohort study

 

Men

Women

Non-smoker

Smoker

Non-smoker

Smoker

HR (95%CI)

HR (95%CI)

HR (95%CI)

HR (95%CI)

All cancers

 Low

1.00

1.00

1.00

1.00

 Moderate

1.00 (0.97–1.02)

0.97 (0.95–1.01)

0.99 (0.96–1.03)

1.22 (0.96–1.55)

 High-to-low

0.96 (0.92–1.00)

1.05 (0.99–1.10)

0.98 (0.93–1.04)

1.06 (0.72–1.54)

 Low-to-high

1.00 (0.95–1.04)

0.99 (0.94–1.05)

0.97 (0.92–1.02)

1.20 (0.83–1.74)

 High

1.01 (0.97–1.06)

1.03 (0.96–1.10)

0.92 (0.87–0.98)

0.95 (0.60–1.50)

Colorectum

 Low

1.00

1.00

1.00

1.00

 Moderate

0.99 (0.93–1.06)

0.89 (0.82–0.96)

0.96 (0.87–1.06)

1.08 (0.53–2.19)

 High-to-low

0.91 (0.81–1.02)

1.08 (0.94–1.25)

0.94 (0.79–1.11)

0.49 (0.12–2.01)

 Low-to-high

1.00 (0.89–1.12)

0.99 (0.86–1.14)

0.97 (0.82–1.14)

0.56 (0.14–2.30)

 High

1.03 (0.92–1.16)

1.02 (0.85–1.21)

0.92 (0.76–1.10)

0.76 (0.18–3.11)

Liver

 Low

1.00

1.00

1.00

1.00

 Moderate

1.03 (0.94–1.11)

0.97 (0.88–1.07)

1.04 (0.87–1.24)

1.23 (0.42–3.59)

 High-to-low

0.95 (0.82–1.11)

1.08 (0.91–1.28)

1.27 (0.99–1.63)

 Low-to-high

1.02 (0.88–1.19)

0.99 (0.82–1.18)

0.80 (0.58–1.09)

1.43 (0.34–6.05)

 High

0.91 (0.77–1.07)

1.19 (0.97–1.47)

1.02 (0.75–1.39)

Lung

 Low

1.00

1.00

1.00

1.00

 Moderate

0.88 (0.80–0.96)

0.88 (0.80–0.95)

1.10 (0.98–1.24)

1.02 (0.49–2.15)

 High-to-low

0.94 (0.81–1.09)

1.08 (0.95–1.23)

1.03 (0.84–1.26)

1.11 (0.45–2.78)

 Low-to-high

1.02 (0.88–1.17)

1.02 (0.90–1.15)

1.00 (0.81–1.23)

2.01 (0.92–4.40)

 High

0.89 (0.76–1.04)

0.94 (0.80–1.11)

1.09 (0.87–1.35)

1.19 (0.37–3.83)

Thyroid

 Low

1.00

1.00

1.00

1.00

 Moderate

0.98 (0.89–1.08)

1.01 (0.88–1.15)

1.03 (0.97–1.09)

1.48 (0.86–2.55)

 High-to-low

0.83 (0.69–1.01)

0.84 (0.62–1.13)

0.98 (0.87–1.11)

1.84 (0.79–4.26)

 Low-to-high

0.77 (0.62–0.97)

0.87 (0.64–1.18)

1.00 (0.89–1.13)

1.43 (0.57–3.56)

 High

0.80 (0.64–1.00)

0.88 (0.62–1.26)

1.01 (0.89–1.14)

0.97 (0.30–3.10)

Breast

 Low

  

1.00

1.00

 Moderate

  

1.06 (0.99–1.14)

1.14 (0.59–2.19)

 High-to-low

  

0.87 (0.74–1.02)

1.42 (0.51–3.93)

 Low-to-high

  

0.87 (0.75–1.01)

1.79 (0.71–4.48)

 High

  

0.81 (0.69–0.95)

1.42 (0.51–3.95)

Corpus uteri

 Low

  

1.00

1.00

 Moderate

  

1.11 (0.91–1.34)

1.66 (0.34–8.11)

 High-to-low

  

1.01 (0.68–1.51)

2.37 (0.29–19.46)

 Low-to-high

  

0.75 (0.48–1.18)

2.45 (0.30–20.12)

 High

  

1.21 (0.82–1.77)

  1. Adjusted for age, income, frequency of alcohol drinking, smoking status, BMI group, and Charlson Comorbidity Index