The relationship between self-perceived fatigue, muscle endurance, and circulating markers of inflammation in participants of the Copenhagen aging and Midlife Biobank (CAMB)

Table 3 Relationships of inflammation with age, self-perceived fatigue, physical activity and muscle endurance

Parameter	hs-CRP			IFN-γ			IL-6			IL-10			TNF-alpha
Parameter	Males	Females	Total	Males	Females	Total	Males	Females	Total	Males	Females	Total	Males	Females	Total
Age	0.03	0.07	0.06	0.10*	0.14^†	0.13^†	0.26^†	0.12*	0.21^†	0.16^†	0.12*	0.16^†	0.17^†	0.17^†	0.20^†
Total Fatigue	0.19^†	0.24^†	0.21^†	0.03	0.10*	0.06	0.29^†	0.26^†	0.27^†	0.06	0.06	0.05	0.09*	0.17^†	0.12^†
General Fatigue	0.11*	0.12*	0.11^†	0.03	0.06	0.04	0.23^†	0.14^†	0.18^†	0.08	-0.01	0.04	0.07	0.09	0.06
Physical Fatigue	0.24^†	0.33^†	0.27^†	0.03	0.11*	-0.02	0.31^†	0.32^†	0.30^†	0.01	-0.02	-0.02	0.08	0.14^†	0.08*
Reduced Activity	0.19^†	0.22^†	0.20^†	0.06	0.08	0.07*	0.29^†	0.30^†	0.29^†	0.07	0.07	0.07*	0.13^†	0.21^†	0.17^†
Reduced motivation	0.12^†	0.15^†	0.14^†	0.02	0.08	0.05	0.14^†	0.17^†	0.16^†	0.04	0.10*	0.07*	0.05	0.13^†	0.10^†
Mental Fatigue	0.03	0.13*	0.08*	-0.03	0.06	0.02	0.08	0.10	0.09^†	0.01	0.13*	0.07*	-0.02	0.14^†	0.05
Physical activity	0.01	-0.11*	-0.04	0.02	0.02	0.02	-0.09	-0.12*	-0.10^†	-0.05	0.03	-0.01	-0.05	-0.06	-0.04
Fatigue Resistance^a	-0.15^†	-0.24^†	-0.19^†	0.01	-0.08	-0.04	-0.11^†	-0.22^†	-0.17^†	0.01	-0.05	-0.04	-0.06	-0.10*	-0.11^†
Grip Work^a	-0.18^†	-0.26^†	-0.21^†	-0.01	-0.09	-0.04	-0.17^†	-0.25^†	-0.19^†	-0.04	-0.06	-0.03	-0.10*	-0.11*	-0.07*

^aCorrected for body weight, values represent Spearman Rho correlation coefficients *p < 0.05, ^† p < 0.01

ISSN: 1861-6909