Alibhai SM, Greenwood C, Payette H (2005) An approach to the management of unintentional weight loss in elderly people. CMAJ 172:773–780
Article
PubMed
Google Scholar
Baggio G, Donazzan S, Monti D, Mari D, Martini S, Gabelli C, Dalla Vestra M, Previato L, Guido M, Pigozzo S, Cortella I, Crepaldi G, Franceschi C (1998) Lipoprotein(a) and lipoprotein profile in healthy centenarians: a reappraisal of vascular risk factors. FASEB J 12:433–437
PubMed
CAS
Google Scholar
Balducci L (2010) Anemia, fatigue and aging. Transfus Clin Biol 17:375–381
Article
PubMed
CAS
Google Scholar
Baumgartner RN, Koehler KM, Gallagher D, Romero L, Heymsfield SB, Ross RR, Garry PJ, Lindeman RD (1998) Epidemiology of sarcopenia among the elderly in New Mexico. Am J Epidemiol 147:755–763
Article
PubMed
CAS
Google Scholar
Bearne LM, Scott DL, Hurley MV (2002) Exercise can reverse quadriceps sensorimotor dysfunction that is associated with rheumatoid arthritis without exacerbating disease activity. Rheumatology (Oxford) 41:157–166
Article
CAS
Google Scholar
Beck AM, Ovesen L, Osler M (1999) The ‘Mini Nutritional Assessment’ (MNA) and the ‘Determine Your Nutritional Health’ Checklist (NSI Checklist) as predictors of morbidity and mortality in an elderly Danish population. Br J Nutr 81:31–36
Article
PubMed
CAS
Google Scholar
Biberstine KJ, Rosenthal RS (1994) Peptidoglycan fragments decrease food intake and body weight gain in rats. Infect Immun 62:3276–3281
PubMed
CAS
Google Scholar
Boyce JM, Shone GR (2006) Effects of ageing on smell and taste. Postgrad Med J 82:239–241
Article
PubMed
CAS
Google Scholar
Braddy KK, Imam SN, Palla KR, Lee TA (2009) Vitamin D deficiency/insufficiency practice patterns in a veterans health administration long-term care population: a retrospective analysis. J Am Med Dir Assoc 10:653–657
Article
PubMed
Google Scholar
Castaneda C, Gordon PL, Uhlin KL, Levey AS, Kehayias JJ, Dwyer JT, Fielding RA, Roubenoff R, Singh MF (2001) Resistance training to counteract the catabolism of a low-protein diet in patients with chronic renal insufficiency. A randomized, controlled trial. Ann Intern Med 135:965–976
PubMed
CAS
Google Scholar
Centers for Disease Control (2003) Public Health and Aging: trends in aging—United States and worldwide. MMWR Morb Mortal Wkly Rep 52:101–104, 106
Google Scholar
Cereda E, Valzolgher L, Pedrolli C (2008) Mini nutritional assessment is a good predictor of functional status in institutionalised elderly at risk of malnutrition. Clin Nutr 27:700–705
Article
PubMed
Google Scholar
Chapman IM (2011) Weight loss in older persons. Med Clin North Am 95:579–593, xi
Article
PubMed
Google Scholar
Chapman I, Parker B, Doran S, Feinle-Bisset C, Wishart J, Lush CW, Chen K, Lacerte C, Burns C, McKay R, Weyer C, Horowitz M (2007) Low-dose pramlintide reduced food intake and meal duration in healthy, normal-weight subjects. Obesity (Silver Spring) 15:1179–1186
Article
CAS
Google Scholar
Cohen HJ, Pieper CF, Harris T, Rao KM, Currie MS (1997) The association of plasma IL-6 levels with functional disability in community-dwelling elderly. J Gerontol A Biol Sci Med Sci 52:M201–M208
Article
PubMed
CAS
Google Scholar
Crimmins E, Vasunilashorn S, Kim JK, Alley D (2008) Biomarkers related to aging in human populations. Adv Clin Chem 46:161–216
Article
PubMed
CAS
Google Scholar
Cuervo M, Ansorena D, Martinez-Gonzalez MA, Garcia A, Astiasaran I, Martinez JA (2009) Impact of global and subjective mini nutritional assessment (MNA) questions on the evaluation of the nutritional status: the role of gender and age. Arch Gerontol Geriatr 49:69–73
Article
PubMed
Google Scholar
de Mutsert R, Grootendorst DC, Boeschoten EW, Brandts H, van Manen JG, Krediet RT, Dekker FW (2009) Subjective global assessment of nutritional status is strongly associated with mortality in chronic dialysis patients. Am J Clin Nutr 89:787–793
Article
PubMed
Google Scholar
Deans C, Wigmore SJ (2005) Systemic inflammation, cachexia and prognosis in patients with cancer. Curr Opin Clin Nutr Metab Care 8:265–269
Article
PubMed
CAS
Google Scholar
Dunne JL, Dahl WJ (2007) A novel solution is needed to correct low nutrient intakes in elderly long-term care residents. Nutr Rev 65:135–138
Article
PubMed
Google Scholar
Dyck MJ, Schumacher JR (2011) Evidence-based practices for the prevention of weight loss in nursing home residents. J Gerontol Nurs 37:22–33, quiz 34–25
Article
PubMed
Google Scholar
Enoki H, Kuzuya M, Masuda Y, Hirakawa Y, Iwata M, Izawa S, Hasegawa J, Iguchi A (2007) Anthropometric measurements as a predictor of mortality of community-dwelling Japanese elderly: the Nagoya Longitudinal Study of Frail Elderly (NLS-FE). Nihon Ronen Igakkai Zasshi 44:212–218
Article
PubMed
Google Scholar
Evans WJ, Morley JE, Argiles J, Bales C, Baracos V, Guttridge D, Jatoi A, Kalantar-Zadeh K, Lochs H, Mantovani G, Marks D, Mitch WE, Muscaritoli M, Najand A, Ponikowski P, Rossi Fanelli F, Schambelan M, Schols A, Schuster M, Thomas D, Wolfe R, Anker SD (2008) Cachexia: A new definition. Clin Nutr 27:793–799
Article
PubMed
CAS
Google Scholar
Fearon KC, Von Meyenfeldt MF, Moses AG, Van Geenen R, Roy A, Gouma DJ, Giacosa A, Van Gossum A, Bauer J, Barber MD, Aaronson NK, Voss AC, Tisdale MJ (2003) Effect of a protein and energy dense N-3 fatty acid enriched oral supplement on loss of weight and lean tissue in cancer cachexia: a randomised double blind trial. Gut 52:1479–1486
Article
PubMed
CAS
Google Scholar
Fielding RA, Vellas B, Evans WJ, Bhasin S, Morley JE, Newman AB, Abellan van Kan G, Andrieu S, Bauer J, Breuille D, Cederholm T, Chandler J, De Meynard C, Donini L, Harris T, Kannt A, Keime Guibert F, Onder G, Papanicolaou D, Rolland Y, Rooks D, Sieber C, Souhami E, Verlaan S, Zamboni M (2011) Sarcopenia: an undiagnosed condition in older adults. Current consensus definition: prevalence, etiology, and consequences. International working group on sarcopenia. J Am Med Dir Assoc 12:249–256
Article
PubMed
Google Scholar
Fuhrman MP, Charney P, Mueller CM (2004) Hepatic proteins and nutrition assessment. J Am Diet Assoc 104:1258–1264
Article
PubMed
CAS
Google Scholar
Gordon JN, Trebble TM, Ellis RD, Duncan HD, Johns T, Goggin PM (2005) Thalidomide in the treatment of cancer cachexia: A randomised placebo controlled trial. Gut 54:540–545
Article
PubMed
CAS
Google Scholar
Gosney M (2003) Are we wasting our money on food supplements in elder care wards? J Adv Nurs 43:275–280
Article
PubMed
Google Scholar
Gruenewald TL, Seeman TE, Karlamangla AS, Sarkisian CA (2009) Allostatic load and frailty in older adults. J Am Geriatr Soc 57:1525–1531
Article
PubMed
Google Scholar
Guigoz Y, Lauque S, Vellas BJ (2002) Identifying the elderly at risk for malnutrition. The Mini Nutritional Assessment. Clin Geriatr Med 18:737–757
Article
PubMed
Google Scholar
Gupta B, Kant S, Mishra R (2010) Subjective global assessment of nutritional status of chronic obstructive pulmonary disease patients on admission. Int J Tuberc Lung Dis 14:500–505
PubMed
CAS
Google Scholar
Harrington M, Gibson S, Cottrell RC (2009) A review and meta-analysis of the effect of weight loss on all-cause mortality risk. Nutr Res Rev 22:93–108
Article
PubMed
Google Scholar
Heiat A, Vaccarino V, Krumholz HM (2001) An evidence-based assessment of federal guidelines for overweight and obesity as they apply to elderly persons. Arch Intern Med 161:1194–1203
Article
PubMed
CAS
Google Scholar
Jiawiwatkul U, Aekplakorn W, Vapattanawong P, Prasartkul P, Poraphakkham Y (2011) Changes in active life expectancy among older Thais: results from the 1997 and 2004 National Health Examination Surveys. Asia Pac J Public Health
Koehler KM (1994) The New Mexico aging process study. Nutr Rev 52:S34–S37
Article
PubMed
CAS
Google Scholar
Ly LP, Jimenez M, Zhuang TN, Celermajer DS, Conway AJ, Handelsman DJ (2001) A double-blind, placebo-controlled, randomized clinical trial of transdermal dihydrotestosterone gel on muscular strength, mobility, and quality of life in older men with partial androgen deficiency. J Clin Endocrinol Metab 86:4078–4088
Article
PubMed
CAS
Google Scholar
MacIntosh CG, Andrews JM, Jones KL, Wishart JM, Morris HA, Jansen JB, Morley JE, Horowitz M, Chapman IM (1999) Effects of age on concentrations of plasma cholecystokinin, glucagon-like peptide 1, and peptide YY and their relation to appetite and pyloric motility. Am J Clin Nutr 69:999–1006
PubMed
CAS
Google Scholar
Maggio M, Guralnik JM, Longo DL, Ferrucci L (2006) Interleukin-6 in aging and chronic disease: a magnificent pathway. J Gerontol A Biol Sci Med Sci 61:575–584
Article
PubMed
Google Scholar
Matsuda T, Doty RL (1995) Regional taste sensitivity to NaCl: Relationship to subject age, tongue locus and area of stimulation. Chem Senses 20:283–290
Article
PubMed
CAS
Google Scholar
Miller MD, Crotty M, Giles LC, Bannerman E, Whitehead C, Cobiac L, Daniels LA, Andrews G (2002) Corrected arm muscle area: An independent predictor of long-term mortality in community-dwelling older adults? J Am Geriatr Soc 50:1272–1277
Article
PubMed
Google Scholar
Milne AC, Avenell A, Potter J (2006) Meta-analysis: protein and energy supplementation in older people. Ann Intern Med 144:37–48
PubMed
CAS
Google Scholar
Morley JE (1997) Anorexia of aging: Physiologic and pathologic. Am J Clin Nutr 66:760–773
PubMed
CAS
Google Scholar
Morley JE (2007) The aging gut: Physiology. Clin Geriatr Med 23:757–767, v-vi
Article
PubMed
Google Scholar
Morley JE (2008) Sarcopenia: diagnosis and treatment. J Nutr Health Aging 12:452–456
Article
PubMed
CAS
Google Scholar
Morley JE, Argiles JM, Evans WJ, Bhasin S, Cella D, Deutz NE, Doehner W, Fearon KC, Ferrucci L, Hellerstein MK, Kalantar-Zadeh K, Lochs H, MacDonald N, Mulligan K, Muscaritoli M, Ponikowski P, Posthauer ME, Rossi Fanelli F, Schambelan M, Schols AM, Schuster MW, Anker SD (2010) Nutritional recommendations for the management of sarcopenia. J Am Med Dir Assoc 11:391–396
Article
PubMed
Google Scholar
Morley JE, Kumar VB, Mattammal MB, Farr S, Morley PM, Flood JF (1996) Inhibition of feeding by a nitric oxide synthase inhibitor: Effects of aging. Eur J Pharmacol 311:15–19
Article
PubMed
CAS
Google Scholar
Morley JE, Silver AJ, Miller DK, Rubenstein LZ (1989) The anorexia of the elderly. Ann N Y Acad Sci 575:50–58, discussion 58–59
Article
PubMed
CAS
Google Scholar
Morley JE, Thomas DR, Wilson MM (2006) Cachexia: pathophysiology and clinical relevance. Am J Clin Nutr 83:735–743
PubMed
CAS
Google Scholar
Nair KS (2000) Age-related changes in muscle. Mayo Clin Proc 75(Suppl):S14–S18
PubMed
Google Scholar
Newman AB, Yanez D, Harris T, Duxbury A, Enright PL, Fried LP (2001) Weight change in old age and its association with mortality. J Am Geriatr Soc 49:1309–1318
Article
PubMed
CAS
Google Scholar
Ooyama K, Kojima K, Aoyama T, Takeuchi H (2009) Decrease of food intake in rats after ingestion of medium-chain triacylglycerol. J Nutr Sci Vitaminol (Tokyo) 55:423–427
Article
CAS
Google Scholar
Pedersen PU (2005) Nutritional care: The effectiveness of actively involving older patients. J Clin Nurs 14:247–255
Article
PubMed
Google Scholar
Perry HM 3rd, Miller DK, Patrick P, Morley JE (2000) Testosterone and leptin in older African-American men: Relationship to age, strength, function, and season. Metabolism 49:1085–1091
Article
PubMed
CAS
Google Scholar
Pillard F, Laoudj-Chenivesse D, Carnac G, Mercier J, Rami J, Riviere D, Rolland Y (2011) Physical activity and sarcopenia. Clin Geriatr Med 27:449–470
Article
PubMed
Google Scholar
Riediger T, Cordani C, Potes CS, Lutz TA (2010) Involvement of nitric oxide in lipopolysaccharide induced anorexia. Pharmacol Biochem Behav 97:112–120
Article
PubMed
CAS
Google Scholar
Rodino-Klapac LR, Haidet AM, Kota J, Handy C, Kaspar BK, Mendell JR (2009) Inhibition of myostatin with emphasis on follistatin as a therapy for muscle disease. Muscle Nerve 39:283–296
Article
PubMed
CAS
Google Scholar
Rodrigues Pereira N, Bandeira Moss M, Assumpcao CR, Cardoso CB, Mann GE, Brunini TM, Mendes-Ribeiro AC (2010) Oxidative stress, l-arginine–nitric oxide and arginase pathways in platelets from adolescents with anorexia nervosa. Blood Cells Mol Dis 44:164–168
Article
PubMed
Google Scholar
Rolland Y, Kim MJ, Gammack JK, Wilson MM, Thomas DR, Morley JE (2006) Office management of weight loss in older persons. Am J Med 119:1019–1026
Article
PubMed
Google Scholar
Roubenoff R, Wilson IB (2001) Effect of resistance training on self-reported physical functioning in HIV infection. Med Sci Sports Exerc 33:1811–1817
Article
PubMed
CAS
Google Scholar
Rudman D, Kutner MH, Rogers CM, Lubin MF, Fleming GA, Bain RP (1981) Impaired growth hormone secretion in the adult population: relation to age and adiposity. J Clin Invest 67:1361–1369
Article
PubMed
CAS
Google Scholar
Sainz N, Rodriguez A, Catalan V, Becerril S, Ramirez B, Gomez-Ambrosi J, Fruhbeck G (2009) Leptin administration favors muscle mass accretion by decreasing FoxO3a and increasing PGC-1alpha in ob/ob mice. PLoS One 4:e6808
Article
PubMed
Google Scholar
Sallis RE (2009) Exercise is medicine and physicians need to prescribe it! Br J Sports Med 43:3–4
Article
PubMed
CAS
Google Scholar
Schiffman SS (1991) Taste and smell losses with age. Bol Asoc Med P R 83:411–414
PubMed
CAS
Google Scholar
Schoenborn CA, Adams PF, Barnes PM (2002) Body weight status of adults: United States, 1997-98, Adv Data, 1-15.
Sih R, Morley JE, Kaiser FE, Perry HM 3rd, Patrick P, Ross C (1997) Testosterone replacement in older hypogonadal men: A 12-month randomized controlled trial. J Clin Endocrinol Metab 82:1661–1667
Article
PubMed
CAS
Google Scholar
Simmons SF, Garcia ET, Cadogan MP, Al-Samarrai NR, Levy-Storms LF, Osterweil D, Schnelle JF (2003) The minimum data set weight-loss quality indicator: Does it reflect differences in care processes related to weight loss? J Am Geriatr Soc 51:1410–1418
Article
PubMed
Google Scholar
Somes GW, Kritchevsky SB, Shorr RI, Pahor M, Applegate WB (2002) Body mass index, weight change, and death in older adults: The systolic hypertension in the elderly program. Am J Epidemiol 156:132–138
Article
PubMed
Google Scholar
Squadrito F, Calapai G, Altavilla D, Cucinotta D, Zingarelli B, Arcoraci V, Campo GM, Caputi AP (1994) Central serotoninergic system involvement in the anorexia induced by NG-nitro-l-arginine, an inhibitor of nitric oxide synthase. Eur J Pharmacol 255:51–55
Article
PubMed
CAS
Google Scholar
Stevens J, Cai J, Pamuk ER, Williamson DF, Thun MJ, Wood JL (1998) The effect of age on the association between body-mass index and mortality. N Engl J Med 338:1–7
Article
PubMed
CAS
Google Scholar
Stratton RJ, King CL, Stroud MA, Jackson AA, Elia M (2006) ‘Malnutrition Universal Screening Tool’ predicts mortality and length of hospital stay in acutely ill elderly. Br J Nutr 95:325–330
Article
PubMed
CAS
Google Scholar
Szulc P, Beck TJ, Marchand F, Delmas PD (2005) Low skeletal muscle mass is associated with poor structural parameters of bone and impaired balance in elderly men—the MINOS study. J Bone Miner Res 20:721–729
Article
PubMed
Google Scholar
Taaffe DR, Pruitt L, Reim J, Hintz RL, Butterfield G, Hoffman AR, Marcus R (1994) Effect of recombinant human growth hormone on the muscle strength response to resistance exercise in elderly men. J Clin Endocrinol Metab 79:1361–1366
Article
PubMed
CAS
Google Scholar
Taniguchi E, Kawaguchi T, Itou M, Oriishi T, Ibi R, Torii M, Yoshida K, Adachi Y, Otsuka M, Uchida Y, Tanaka S, Takakura M, Sata M (2011) Subjective global assessment is not sufficient to screen patients with defective hepatic metabolism. Nutrition 27:282–286
Article
PubMed
Google Scholar
Tedla FM, Friedman EA (2008) The trend toward geriatric nephrology. Prim Care 35:515–530, vii
Article
PubMed
Google Scholar
Thomas DR (2006) Guidelines for the use of orexigenic drugs in long-term care. Nutr Clin Pract 21:82–87
Article
PubMed
Google Scholar
Thomas DR (2007) Loss of skeletal muscle mass in aging: Examining the relationship of starvation, sarcopenia and cachexia. Clin Nutr 26:389–399
Article
PubMed
Google Scholar
Tsai AC, Chou YT, Chang TL (2011) Usefulness of the Mini Nutritional Assessment (MNA) in predicting the nutritional status of people with mental disorders in Taiwan. J Clin Nurs 20:341–350
Article
PubMed
Google Scholar
Tsai AC, Chou YT, Chang TL, Chang-Lee SN, Tsay SF (2009) A modified Mini Nutritional Assessment without BMI can effectively assess the nutritional status of neuropsychiatric patients. J Clin Nurs 18:1916–1922
Article
PubMed
Google Scholar
Tsai AC, Shih CL (2009) A population-specific Mini-Nutritional Assessment can effectively grade the nutritional status of stroke rehabilitation patients in Taiwan. J Clin Nurs 18:82–88
Article
PubMed
Google Scholar
Vignini A, Canibus P, Nanetti L, Montecchiani G, Faloia E, Cester AM, Boscaro M, Mazzanti L (2008) Lipoproteins obtained from anorexia nervosa patients induce higher oxidative stress in U373MG astrocytes through nitric oxide production. Neuromolecular Med 10:17–23
Article
PubMed
CAS
Google Scholar
Villareal DT, Apovian CM, Kushner RF, Klein S (2005) Obesity in older adults: Technical review and position statement of the American Society for Nutrition and NAASO. The Obesity Society. Am J Clin Nutr 82:923–934
PubMed
CAS
Google Scholar
Visser M, Newman AB, Nevitt MC, Kritchevsky SB, Stamm EB, Goodpaster BH, Harris TB (2000) Reexamining the sarcopenia hypothesis. Muscle mass versus muscle strength. Health, Aging, and Body Composition Study Research Group. Ann N Y Acad Sci 904:456–461
Article
PubMed
CAS
Google Scholar
Visvanathan R, Chapman IM (2009) Undernutrition and anorexia in the older person. Gastroenterol Clin North Am 38:393–409
Article
PubMed
Google Scholar
Visvanathan R, Macintosh C, Callary M, Penhall R, Horowitz M, Chapman I (2003) The nutritional status of 250 older Australian recipients of domiciliary care services and its association with outcomes at 12 months. J Am Geriatr Soc 51:1007–1011
Article
PubMed
Google Scholar
Wallace JI, Schwartz RS, LaCroix AZ, Uhlmann RF, Pearlman RA (1995) Involuntary weight loss in older outpatients: incidence and clinical significance. J Am Geriatr Soc 43:329–337
PubMed
CAS
Google Scholar
Walston J, Hadley EC, Ferrucci L, Guralnik JM, Newman AB, Studenski SA, Ershler WB, Harris T, Fried LP (2006) Research agenda for frailty in older adults: toward a better understanding of physiology and etiology: summary from the American Geriatrics Society/National Institute on Aging Research conference on frailty in older adults. J Am Geriatr Soc 54:991–1001
Article
PubMed
Google Scholar
Wansink B, Payne CR (2007) Counting bones: Environmental cues that decrease food intake. Percept Mot Skills 104:273–276
Article
PubMed
Google Scholar
Weiffenbach JM, Cowart BJ, Baum BJ (1986) Taste intensity perception in aging. J Gerontol 41:460–468
PubMed
CAS
Google Scholar
Weiss CO, Boyd CM, Yu Q, Wolff JL, Leff B (2007) Patterns of prevalent major chronic disease among older adults in the United States. JAMA 298:1160–1162
PubMed
CAS
Google Scholar
Wilson MM, Morley JE (2003) Invited review: Aging and energy balance. J Appl Physiol 95:1728–1736
PubMed
CAS
Google Scholar
Wilson MM, Thomas DR, Rubenstein LZ, Chibnall JT, Anderson S, Baxi A, Diebold MR, Morley JE (2005) Appetite assessment: Simple appetite questionnaire predicts weight loss in community-dwelling adults and nursing home residents. Am J Clin Nutr 82:1074–1081
PubMed
CAS
Google Scholar
Wurtman JJ, Lieberman H, Tsay R, Nader T, Chew B (1988) Calorie and nutrient intakes of elderly and young subjects measured under identical conditions. J Gerontol 43:B174–B180
PubMed
CAS
Google Scholar
Zoico E, Di Francesco V, Guralnik JM, Mazzali G, Bortolani A, Guariento S, Sergi G, Bosello O, Zamboni M (2004) Physical disability and muscular strength in relation to obesity and different body composition indexes in a sample of healthy elderly women. Int J Obes Relat Metab Disord 28:234–241
PubMed
CAS
Google Scholar